Mielinolisis pontina cerebral pdf

Osmotic demyelination syndrome refers to acute demyelination seen in the setting of osmotic changes, typically with the rapid correction of hyponatremia. Mielinolisis pontina central e hiponatremia perioperatoria. Mielinolisis central pontina tras sindrome neuroleptico. Hospital general regional 110 imss university of arizona.

Acute neurological complications after liver transplantation with particular reference to intraoperative cerebral air embolus. It is the more recent term replacing central pontine myelinolysis, recognizing that extrapontine structures can also be affected, previously known as extrapontine myelinolysis. West, central myelinolysis in a patient with hyponatraemia. One of the well recognized stimuli for central pontine myelinosis cpm is the rapid correction of chronic hyponatraemia. As such the condition is described in the osmotic demyelination syndrome article. Extrapontine myelinolysis radiology reference article.

Chronic alcoholism or rapid correction of hyponatremia was present in over 75% of cases. Central pontine myelinolysis radiology reference article. Pdf central pontine myelinolysis is a demyelinating lesion in the basis pontis which in most cases is caused by a rapid correction of hyponatremia. Antemortem computed tomography ct had been performed in nine, and ante or postmortem magnetic resonance mr imaging in 11. Extrapontine myelinolysis epm is one of the complications occurring secondary to rapid correction of hyponatremia, and is, along with central pontine myelinolysis encompassed by the more recent term osmotic demyelination syndrome in the vast majority of cases it is associated with central pontine myelinolysis but it can also rarely occur as an isolated entity. Central pontine myelinolysis cpm is the most severe neurological complication after liver transplantation and apparently is not. Central pontine myelinolysis cpm is now more commonly referred to as osmotic demyelination syndrome, which recognizes that the same phenomenon is also seen in other areas of the brain previously known as extrapontine myelinolysis. Pdf mielinolisis pontina central e hiponatremia perioperatoria. Pdf mielinolisis central pontina en trasplante hepatico. Central pontine myelinosis has been associated with chronic alcoholism, chronic nutritional deficiencies, hepatic failure, chronic renal failure and systemic disorders which result in electrolyte imbalance 1, 3. It is predominately iatrogenic treatmentinduced, and is characterized by acute paralysis, dysphagia difficulty swallowing, dysarthria difficulty speaking, and other neurological symptoms. Conventionally this has been perceived to lead to pontine glial cell swelling through osmosis and eventually to cell death.

Burns cause injuries that affect the integrity of the skin and can damage, among other systems, the neurological system, as some time after they take place, vasodilatation and marked cerebral edema with diffuse neuronal degeneration. Central pontine myelinolysis cpm is a neurological condition involving severe damage to the myelin sheath of nerve cells in the pons an area of the brainstem. Central pontine myelinolysis after liver transplantation. Osmotic demyelination syndrome radiology reference. Mielinolisis extrapontina secundaria a hiponatremia por crisis.